Mescaline

Background

Peyote
  • Psychedelic phenethylamine , naturally occurring in peyote and other cacti
  • Similar to, but chemically distinct from and less potent than LSD
  • Thought to be a serotonin agonist
  • Sold as dried cactus parts or "buttons"
  • Used in religious ceremonies by some indigenous Central and South american peoples.

Clinical Features

  • Onset 30-60 minutes, lasts 5-12 hours (though wide individual variability)
  • Euphoria, energy, esoteric/spiritual experiences
  • Altered sensorium, altered sense of time, extreme focus or distractibility, hallucinations
  • Nausea/vomiting, abdominal pain
  • Adrenergic stimulation: mydriasis, mild tachycardia, mild hypertension, hyperthermia
  • Dizziness, headache

Differential Diagnosis

Hallucinogens

Dissociative drugs

Evaluation

  • Not detected on routine drug screens
  • Evaluate for other organic causes of hallucinations or hyperadrenergic symptoms
  • Evaluate for co-ingestions

Management

  • Supportive care
  • Not usually associated with significant morbidity/mortality

Disposition

See Also

External Links

References

Authors:

Claire