Erythema infectiosum
Revision as of 10:42, 26 April 2015 by Rossdonaldson1 (talk | contribs)
Background
- Caused by Parvovirus B19
- May precipitate aplastic crisis in patients with sickle cell disease
- Disruption of hematopoiesis
- Infection in pregnancy
- Hydrops fetalis and fetal loss
Clinical Features
- Initially mild URI-type symptoms
- "Slapped cheeks" rash
- Abrupt appearance on day 3-4
- Spares eyelids and chin
- Lasts 4-5 days
- Abrupt appearance on day 3-4
- Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
- distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
- May last 1 week
- Rash may recur within 3 week period
- Associated symptoms include fever, HA, sore throat, cough, coryza, N/V
Differential Diagnosis
Pediatric Rash
- Atopic dermatitis
- Bed bugs
- Contact dermatitis
- Drug rash
- Erythema infectiosum (Fifth disease)
- Hand-foot-and-mouth disease
- Henoch-schonlein purpura (HSP)
- Herpangina
- Herpes simplex virus (HSV)
- Infectious mononucleosis
- Meningitis
- Measles
- Molluscum contagiosum
- Roseola infantum
- Rubella (German measles)
- Scabies
- Scarlet fever
- Smallpox
- Varicella (Chickenpox)
Diagnosis
- Normally clinical
Management
- Symptomatic therapy
Complications
- Symmetric Polyarthropathy
- Myocarditis
- Pericarditis
- Glomerulonephritis
- Focal Glomerulosclerosis