Drug induced aseptic meningitis: Difference between revisions
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**[[Methylprednisolone acetate]]
**[[Methylprednisolone acetate]]
**[[Allopurinol]]
**[[Allopurinol]]
==Diagnosis==
*Drug history with focus on time of ingestion and symptom onset
*CSF studies
**Pleiocytosis (primarily neutrophilic)
**Elevated protein levels
**Normal glucose
**Negative cultures
*Challenge test with suspected drug
**Only confirmatory test
**Requires informed written consent
**Due to associated risk, should only be done if suspected drug is irreplaceable
==Clinical presentation==
==Clinical presentation==
*[[Headache]]
*[[Headache]]

Revision as of 18:32, 1 September 2017

Background

  • Abbreviation: DIAM
  • Two proposed mechanisms
    • Direct meningeal irritation by intrathecal drug
    • Hypersensitivity reaction to drug (type III and IV)

Causes

Clinical presentation

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