Erythema infectiosum: Difference between revisions

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*Caused by parvovirus B19
==Background==
*"Slapped cheeks" rash
*Also known as "Fifth disease"
**Abrupt appeance
*Caused by [[Parvovirus B19]]
**Spares eyelids and chin
**Infection in pregnancy can → [[Hydrops fetalis]], fetal anemia, and fetal loss
**Lasts 4-5d
**May precipitate [[aplastic crisis]] in patients with [[sickle cell disease]]
*Macular erythema develops on trunk/limbs 2d after apperance of facial rash
 
**May last 1wk
==Clinical Features==
*Assoc symptoms include fever, HA, sore throat, cough, coryza, N/V
*Initially mild [[URI]]-type symptoms
**Malaise, myalgias, and headache 7-10 days prior to rash <ref>Sara Bode; Contagious Exanthematous Diseases. ''Quick References 2022''; 10.1542/aap.ppcqr.396150</ref>
*"Slapped cheeks" [[rash]]
**Abrupt appearance on day 3-4
***Spares eyelids and chin
**Lasts 4-5 days
*Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
**Distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
**May last 1 week
**Rash may recur within 3 week period
*Papulopurpuric glove-and-sock syndrome
**[[Pruritus|Pruritic]] or painful [[petechiae]]/purpura limited to the hands and feet. <ref> Shirk A, Sorrentino A. Viral Exanthems. In: Schafermeyer R, Tenenbein M, Macias CG, Sharieff GQ, Yamamoto LG. eds. Strange and Schafermeyer's Pediatric Emergency Medicine, 4e. New York, NY: McGraw-Hill; 2015 </ref>
*Associated symptoms include [[fever]], [[headache]], [[sore throat]], [[cough]], coryza, [[nausea and vomiting]]
 
[[File:Fifth disease.jpg|thumb|Fifths Disease]]
 
==Differential Diagnosis==
{{Peds Rash DDX}}
 
==Evaluation==
*Clinical diagnosis, based on history and physical exam
 
==Management==
*Symptomatic
 
==Disposition==
*Discharge most patients
**Referral to maternal-fetal medicine specialist for infection in pregnancy
*Admit if [[aplastic crisis]]
 
==Complications==
*Symmetric Polyarthropathy
*[[Myocarditis]]
*[[Pericarditis]]
*[[Glomerulonephritis]]
*Focal Glomerulosclerosis


==See Also==
==See Also==
[[Pediatric Rashes]]
*[[Pediatric Rashes]]
 
==References==
<References/>


[[Category:Derm]]
[[Category:Dermatology]]
[[Category:ID]]
[[Category:ID]]
[[Category:Peds]]
[[Category:Pediatrics]]

Latest revision as of 20:24, 2 November 2022

Background

Clinical Features

  • Initially mild URI-type symptoms
    • Malaise, myalgias, and headache 7-10 days prior to rash [1]
  • "Slapped cheeks" rash
    • Abrupt appearance on day 3-4
      • Spares eyelids and chin
    • Lasts 4-5 days
  • Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
    • Distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
    • May last 1 week
    • Rash may recur within 3 week period
  • Papulopurpuric glove-and-sock syndrome
  • Associated symptoms include fever, headache, sore throat, cough, coryza, nausea and vomiting
Fifths Disease

Differential Diagnosis

Pediatric Rash

Evaluation

  • Clinical diagnosis, based on history and physical exam

Management

  • Symptomatic

Disposition

  • Discharge most patients
    • Referral to maternal-fetal medicine specialist for infection in pregnancy
  • Admit if aplastic crisis

Complications

See Also

References

  1. ↑ Sara Bode; Contagious Exanthematous Diseases. Quick References 2022; 10.1542/aap.ppcqr.396150
  2. ↑ Shirk A, Sorrentino A. Viral Exanthems. In: Schafermeyer R, Tenenbein M, Macias CG, Sharieff GQ, Yamamoto LG. eds. Strange and Schafermeyer's Pediatric Emergency Medicine, 4e. New York, NY: McGraw-Hill; 2015
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