Erythema infectiosum: Difference between revisions
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==Background== | ==Background== | ||
*Caused by | *Caused by Parvovirus B19 | ||
*May precipitate aplastic crisis in | *May precipitate aplastic crisis in patients with sickle cell disease | ||
*Infection in pregnancy | **Disruption of hematopoiesis | ||
*Infection in pregnancy | |||
**Hydrops fetalis and fetal loss | |||
==Clinical Features== | ==Clinical Features== | ||
*Initially mild URI-type symptoms | |||
*"Slapped cheeks" rash | *"Slapped cheeks" rash | ||
**Abrupt | **Abrupt appearance on day 3-4 | ||
**Spares eyelids and chin | ***Spares eyelids and chin | ||
**Lasts 4- | **Lasts 4-5 days | ||
*Macular erythema develops on trunk/limbs | *Macular erythema develops on trunk/limbs 2 days after appearance of facial rash | ||
**distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance | **distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance | ||
**May last | **May last 1 week | ||
**Rash may recur within 3 week period | **Rash may recur within 3 week period | ||
* | *Associated symptoms include fever, HA, sore throat, cough, coryza, N/V | ||
==Complications== | |||
*Symmetric Polyarthropathy | |||
*[[Myocarditis]] | |||
*[[Pericarditis]] | |||
*[[Glomerulonephritis]] | |||
*Focal Glomerulosclerosis | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 04:19, 4 January 2015
Background
- Caused by Parvovirus B19
- May precipitate aplastic crisis in patients with sickle cell disease
- Disruption of hematopoiesis
- Infection in pregnancy
- Hydrops fetalis and fetal loss
Clinical Features
- Initially mild URI-type symptoms
- "Slapped cheeks" rash
- Abrupt appearance on day 3-4
- Spares eyelids and chin
- Lasts 4-5 days
- Abrupt appearance on day 3-4
- Macular erythema develops on trunk/limbs 2 days after appearance of facial rash
- distinctive aspect of rash: faces with central clearing, giving a reticulated or lacy appearance
- May last 1 week
- Rash may recur within 3 week period
- Associated symptoms include fever, HA, sore throat, cough, coryza, N/V
Complications
- Symmetric Polyarthropathy
- Myocarditis
- Pericarditis
- Glomerulonephritis
- Focal Glomerulosclerosis
Differential Diagnosis
Pediatric Rash
- Atopic dermatitis
- Bed bugs
- Contact dermatitis
- Drug rash
- Erythema infectiosum (Fifth disease)
- Hand-foot-and-mouth disease
- Henoch-schonlein purpura (HSP)
- Herpangina
- Herpes simplex virus (HSV)
- Infectious mononucleosis
- Meningitis
- Measles
- Molluscum contagiosum
- Roseola infantum
- Rubella (German measles)
- Scabies
- Scarlet fever
- Smallpox
- Varicella (Chickenpox)
Management
- Symptomatic therapy