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P450

Contents

  • 1 Background
  • 2 Antimicrobials
    • 2.1 Avoid /P450 Inhibitors
    • 2.2 Use
  • 3 Significant P450 Inhibitors in General
  • 4 Significant P450 Inducers in General

Background

Coumadin

Antimicrobials

Avoid /P450 Inhibitors

  • Quinolones, especially levofloxacin
  • Macrolides, especially erythromycin
  • Bactrim and sulfonamides
  • Flagyl
  • Nafcillin, oxacillin

Use

  • Azithromycin
  • Gentamicin
  • Cephalosporin, aminopenicillins
  • Nitrofurantoin
  • Clindamycin
  • Vancomycin

Significant P450 Inhibitors in General

  • Grapefruit juice
  • Valproate]
  • INH
  • Protease inhibitors (-navir, i.e. ritonavir)
  • SSRIs, except escitalopram
  • Amiodarone
  • Fluoroquinolones
  • Sulfonamides
  • Macrolides
  • Cimetidine
  • Omeprazole
  • Ketoconazole
  • Acute ETOH

Significant P450 Inducers in General

  • Phenytoin
  • Carbamazepine
  • Ethosuximide
  • Quinidine/quinine
  • Rifampin
  • Griseofulvin
  • Glucocorticoids
  • Barbiturates
  • St. John's wort
  • Chronic EtOH
  • Tobacco smoking
Retrieved from "https://www.wikem.org/w/index.php?title=P450&oldid=204287"
Category:
  • Pharmacology
Authors:
  • Claire
  • Kevin Lu
  • Daniel Ostermayer
  • robot
  • Ross Donaldson
  • Privacy policy
  • About WikEM
  • Disclaimers
This page was last edited 01:28, 27 January 2019 by Claire. Donate