Aplastic anemia

Background

Clinical Features

  • Anemia
    • Weakness, fatigue, dyspnea
  • Thrombocytopenia
    • Mucosal bleeding, petechiae
  • Neutropenia
    • Recurrent infections, fever

Differential Diagnosis

Evaluation

  • CBC: pancytopenia
  • Reticulocyte count: reduced or absent
  • Peripheral smear

Management

  • Transfuse PRBCs/platelets as needed for severe anemia/thrombocytopenia
  • Antimicrobials if febrile and neutropenic

Disposition

See Also

External Links

References