Benzodiazepines: Difference between revisions
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*Binding results in inhibition of neuronal firing | *Binding results in inhibition of neuronal firing | ||
== | ==Table== | ||
{| class="wikitable" | {| class="wikitable" | ||
| align="center" style="background:#f0f0f0;"|'''Generic (Trade Name)''' | | align="center" style="background:#f0f0f0;"|'''Generic (Trade Name)''' | ||
| align="center" style="background:#f0f0f0;"|'''Oral Dose''' | | align="center" style="background:#f0f0f0;"|'''Equivalent Oral Dose''' | ||
| align="center" style="background:#f0f0f0;"|'''Onset''' | |||
| align="center" style="background:#f0f0f0;"|'''Duration''' | |||
|- | |- | ||
| [[Alprazolam]] (Xanax)||0. | | [[Alprazolam]] (Xanax)||0.5mg|| || | ||
|- | |- | ||
| [[Chlordiazepoxide]] (Librium)|| | | [[Chlordiazepoxide]] (Librium)||25mg|| || | ||
|- | |- | ||
| [[Diazepam]] (Valium)||5 | | [[Diazepam]] (Valium)||5mg||2-5 min (IV) || | ||
|- | |- | ||
| [[Flurazepam]] (Dalmane)|| | | [[Flurazepam]] (Dalmane)||15mg|| || | ||
|- | |- | ||
| [[Lorazepam]] (Ativan)|| | | [[Lorazepam]] (Ativan)||1mg||5-20 min (IV); 15-30 min (IM)||6-8 H | ||
|- | |- | ||
| [[Midazolam]] (Versed)|| | | [[Midazolam]] (Versed)||5mg||15 min (IM)||2 H | ||
|- | |- | ||
| [[Oxazepam]] (Serax)|| | | [[Oxazepam]] (Serax)||15mg|| || | ||
|} | |} | ||
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*[[Seizure#Treatment|Seizures]] | *[[Seizure#Treatment|Seizures]] | ||
*[[Alcohol Withdrawal]] | *[[Alcohol Withdrawal]] | ||
*Panic | *[[Panic attack|Panic disorder]], Generalized Anxiety Disorder, Anxiety | ||
*[[Insomnia]] | |||
*Insomnia | |||
*Muscle Spasms | *Muscle Spasms | ||
| Line 36: | Line 36: | ||
*[[Benzodiazepine Toxicity]] | *[[Benzodiazepine Toxicity]] | ||
*[[Intranasal Sedation]] | *[[Intranasal Sedation]] | ||
*[[Sedation (main)]] | |||
==References== | ==References== | ||
<references/> | <references/> | ||
[[Category:Pharmacology]] | [[Category:Pharmacology]] [[Category:Neurology]] [[Category:Psychiatry]] | ||
Latest revision as of 23:16, 21 November 2020
Background
- Class of GABA Receptor Agonists
- Binding results in inhibition of neuronal firing
Table
| Generic (Trade Name) | Equivalent Oral Dose | Onset | Duration |
| Alprazolam (Xanax) | 0.5mg | ||
| Chlordiazepoxide (Librium) | 25mg | ||
| Diazepam (Valium) | 5mg | 2-5 min (IV) | |
| Flurazepam (Dalmane) | 15mg | ||
| Lorazepam (Ativan) | 1mg | 5-20 min (IV); 15-30 min (IM) | 6-8 H |
| Midazolam (Versed) | 5mg | 15 min (IM) | 2 H |
| Oxazepam (Serax) | 15mg |
Uses
- Sedation
- Seizures
- Alcohol Withdrawal
- Panic disorder, Generalized Anxiety Disorder, Anxiety
- Insomnia
- Muscle Spasms