Alpha blockers: Difference between revisions
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===Mixed=== | ===Mixed=== | ||
*The agents [[carvedilol]] and [[labetalol]] are both α- and [[ | *The agents [[carvedilol]] and [[labetalol]] are both α- and [[β-blocker|β-blockers]]. | ||
==Uses== | ==Uses== | ||
Revision as of 15:41, 26 July 2017
Background
- Also known as α-blockers
- &α;1-blockers act on &α;1-adrenoceptors
- &α;2-blockers act on &α;2-adrenoceptors
- Act as neutral antagonists or inverse agonists of &α;-adrenergic receptors (α-adrenoceptors)
Medications
Non-selective
- Phenoxybenzamine
- Phentolamine
- Tolazoline
- Trazodone
- Typical and atypical antipsychotics
Selective α 1
Selective α 2
Mixed
- The agents carvedilol and labetalol are both α- and β-blockers.
Uses
- hypertension
- Raynaud's disease
- scleroderma
- generalized anxiety disorder
- panic disorder
- posttraumatic stress disorder
- benign prostatic hyperplasia