P450: Difference between revisions

Latest revision as of 09:13, 22 March 2026

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-Coumadin
+==Background==
+[[Coumadin]]
+==Antimicrobials==
+===Avoid /[[P450]] Inhibitors===
+*[[Quinolones]], especially [[levofloxacin]]
+*[[Macrolides]], especially [[erythromycin]]
+*[[Bactrim]] and sulfonamides
+*[[Flagyl]]
+*[[Nafcillin]], [[oxacillin]]
-Avoid
+===Use===
+*[[Azithromycin]]
+*[[Gentamicin]]
+*[[Cephalosporin]], [[aminopenicillins]]
+*[[Nitrofurantoin]]
+*[[Clindamycin]]
+*[[Vancomycin]]
-Quinolones, esp levoflox
+==Significant [[P450]] Inhibitors in General==
+*Grapefruit juice
+*[[Valproate]]]
+*[[INH]]
+*Protease inhibitors (-navir, i.e. ritonavir)
+*[[SSRIs]], except escitalopram
+*[[Amiodarone]]
+*[[Fluoroquinolones]]
+*[[Sulfonamides]]
+*[[Macrolides]]
+*[[Cimetidine]]
+*[[Omeprazole]]
+*[[Ketoconazole]]
+*Acute [[ETOH]]
-Macrolides, esp erythromycin
+==Significant [[P450]] Inducers in General==
+*[[Phenytoin]]
+*[[Carbamazepine]]
+*[[Ethosuximide]]
+*[[Quinidine]]/[[quinine]]
+*[[Rifampin]]
+*[[Griseofulvin]]
+*[[Glucocorticoids]]
+*[[Barbiturates]]
+*St. John's wort
+*Chronic EtOH
+*[[Tobacco]] smoking
-Bactrim
+==See Also==
+*[[Drug levels]]
+*[[Drug interactions]]
+*[[Pharmacology]]
-Flagyl
+==References==
+<references/>
-Nafcillin, oxacillin
+[[Category:Pharmacology]]
-Use
-Azithro
-Gentamicin
-Cephalosporin, aminopenicillins
-Nitrofurantoin
-Clinda
-Vanc
-[[Category:Drugs]]