Fever of unknown origin (peds): Difference between revisions

Revision as of 15:59, 22 March 2016

Prolonged fever of unknown origin without identified cause generally has favorable prognosis.

Original definition^[1]
- Fever >38.3 C on several occasions
- Lasting for at least 3 weeks
- No clear diagnosis after 1 week inpatient workup
Newer definition^[2] - "Prolonged fever" with:
- 3 outpatient visits without identifying a cause or
- 3 inpatient days without identifying a cause or
- 1 week of “intelligent and invasive” ambulatory investigation

Infection
- Bacterial
  - Adenitis
  - Endocarditis
  - Mastoiditis
  - Occult abscess
  - Pyelonephritis
  - Sinusitis
  - Tb
- Viral
  - CMV
  - Hep A,B, C
  - Mono
- Chlamydial
  - Lymphogranuloma venereum
  - Psittacosis
- Mycoplasmal
- Fungal
  - Blastomycosis
  - Cysticercosis
  - Histoplasmosis
  - Rickettsial
    - Q fever
    - Rocky Mt
  - Parasitic
    - Malaria
    - Toxo
Non-infectious Inflammatory
- JRA
- LSE
- Regional enteritis
- Rheumatic fever
- Ulcerative colitis
- Vasculitis
Malignancy
- Leukemia
- Lymphoma
- Neuroblastoma
- Wilm's tumor
Drug Induced
- Antibiotics
- Anticonvulsants
- Anti TB
- Procainamide
- Quinidine
- Serum sickness
Misc
- AIDS
- CNS
- Environmental
- Factitious
- Familial dysautonomia
- Kawasaki
- PE
- Serial infections
- Thyrotoxicosis

↑ Kaya A, Ergul N, Kaya SY, et al. The management and the diagnosis of fever of unknown origin. Expert Rev Anti Infect Ther. 2013 Aug;11(8):805-15.
↑ Durack DT, Street AC. Fever of unknown origin--reexamined and redefined. Curr Clin Top Infect Dis. 1991;11:35-51.

Authors:

Revision as of 06:00, 10 August 2015 (view source) Mholtz (talk \| contribs) No edit summary ← Older edit		Revision as of 15:59, 22 March 2016 (view source) Ostermayer (talk \| contribs) (Text replacement - "Category:Peds" to "Category:Pediatrics") Newer edit →
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