Antiarrhythmics: Difference between revisions
Ostermayer (talk | contribs) No edit summary |
Neil.m.young (talk | contribs) (Text replacement - "beta blocker" to "β-blocker") |
||
| (23 intermediate revisions by 5 users not shown) | |||
| Line 1: | Line 1: | ||
==Table== | |||
== | |||
{| class="wikitable" | {| class="wikitable" style="width: 641px; height: 711px;" | ||
|- | |- | ||
! Class | ! Class | ||
| Line 28: | Line 13: | ||
| | | | ||
*Quinidine | *Quinidine | ||
*[[Procainamide]] | *[[Procainamide]] | ||
*Disopyramide | *Disopyramide | ||
| Line 41: | Line 26: | ||
| | | | ||
| | | | ||
*[[Lidocaine]] | *[[Lidocaine]] | ||
*Phenytoin | *Phenytoin | ||
*Mexiletine | *Mexiletine | ||
| Line 50: | Line 35: | ||
*treatment and prevention during and immediately after Myocardial infarction, though this practice is now discouraged given the increased risk of Asystole | *treatment and prevention during and immediately after Myocardial infarction, though this practice is now discouraged given the increased risk of Asystole | ||
*Ventricular tachycardia | *Ventricular tachycardia | ||
*[[ | *[[Atrial Fibrillation (Main)|Atrial fibrillation]] | ||
|- | |- | ||
| Line 56: | Line 41: | ||
| | | | ||
| | | | ||
*Flecainide | *[[Flecainide]] | ||
*Propafenone | *Propafenone | ||
*Moricizine | *Moricizine | ||
| Line 68: | Line 53: | ||
|- | |- | ||
! II | ! II | ||
| Beta-blockers | | [[Beta-blockers]] | ||
| | | | ||
*Propranolol | *Propranolol | ||
*[[Esmolol]] | *[[Esmolol]] | ||
*Timolol | *Timolol | ||
*Metoprolol | *[[Metoprolol]] | ||
*Atenolol | *[[Atenolol]] | ||
*Bisoprolol | *Bisoprolol | ||
*[[Labetalol]] | *[[Labetalol]] | ||
| Line 87: | Line 72: | ||
| | | | ||
| | | | ||
*[[Amiodarone]] | *[[Amiodarone]] | ||
*[[Sotalol]] | *[[Sotalol]] | ||
*[[Ibutilide]] | *[[Ibutilide]] | ||
*Dofetilide | *Dofetilide | ||
*Dronedarone | *Dronedarone | ||
| Line 97: | Line 82: | ||
K<sup>+</sup> channel blocker | K<sup>+</sup> channel blocker | ||
Sotalol is also a | Sotalol is also a β-blocker | ||
Amiodarone has Class I, II, and III activity | Amiodarone has Class I, II, and III activity | ||
| Line 104: | Line 89: | ||
*In [[Wolf Parkinson White (WPW)]] | *In [[Wolf Parkinson White (WPW)]] | ||
*(sotalol:) Ventricular tachycardias and Atrial fibrillation | *(sotalol:) Ventricular tachycardias and Atrial fibrillation | ||
*(Ibutilide:) Atrial flutter and [[ | *(Ibutilide:) Atrial flutter and [[Atrial Fibrillation (Main)|Atrial fibrillation]] | ||
|- | |- | ||
| Line 116: | Line 101: | ||
| | | | ||
*prevent recurrence of Paroxysmal supraventricular tachycardia | *prevent recurrence of Paroxysmal supraventricular tachycardia | ||
*reduce Ventricular rate in patients with [[ | *reduce Ventricular rate in patients with [[Atrial Fibrillation (Main)|Atrial fibrillation]] | ||
|- | |- | ||
| Line 122: | Line 107: | ||
| | | | ||
| | | | ||
*[[Adenosine]] | *[[Adenosine]] | ||
*[[Digoxin]] | *[[Digoxin]] | ||
*[[Magnesium]] | *[[Magnesium sulfate]] | ||
| Work by other or unknown mechanisms (Direct nodal inhibition). | | Work by other or unknown mechanisms (Direct nodal inhibition). | ||
| Line 130: | Line 115: | ||
Used in supraventricular arrhythmias, | Used in supraventricular arrhythmias, | ||
Or in the case of | Or in the case of [[magnesium sulfate]], used in [[torsade de pointes]]. | ||
|} | |} | ||
==See Also== | |||
*[[Arrhythmias (DDX)]] | |||
*[[Atropine]] | |||
*[[Isoproterenol]] | |||
== | ==References== | ||
<references/> | |||
* | *Katzung & Trevor's Pharmacology | ||
[[Category:Pharmacology]] [[Category:Cardiology]] | |||
[[Category: | |||
[[Category: | |||
Latest revision as of 18:13, 14 August 2017
Table
| Class | Known as | Examples | Mechanism | Clinical uses |
|---|---|---|---|---|
| Ia | fast-channel blockers-Affect QRS complex |
|
(Na+) channel block (intermediate association/dissociation) |
|
| Ib- Do not affect QRS complex |
|
(Na+) channel block (fast association/dissociation) |
| |
| Ic |
|
(Na+) channel block (slow association/dissociation) |
| |
| II | Beta-blockers |
|
beta blocking Propranolol also shows some class I action |
|
| III |
|
K+ channel blocker Sotalol is also a β-blocker Amiodarone has Class I, II, and III activity |
| |
| IV | slow-channel blockers |
|
Ca2+ channel blocker |
|
| V | Work by other or unknown mechanisms (Direct nodal inhibition). |
Used in supraventricular arrhythmias, Or in the case of magnesium sulfate, used in torsade de pointes. |
See Also
References
- Katzung & Trevor's Pharmacology