Metoprolol

General

  • Type: Beta blockers
  • Dosage Forms: Tablet: 25 mg, 37.5 mg, 50 mg, 75mg, 100 mg. IV: variable
  • Common Trade Names: Lopressor

Adult Dosing

Hypertension

  • 50-200 mg PO bid

CHF

  • 12.5-100 mg PO bid

Migraine prophylaxis

  • 25-100 mg PO bid

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug
  • Sinus bradycardia
  • AV blocks
  • decompensated acute CHF
  • cardiogenic shock
  • hypotension

Adverse Reactions

Serious

  • CHF
  • bradycardia
  • AV block
  • bronchospasm

Common

  • fatigue
  • dizziness
  • depression
  • dyspnea

Pharmacology

  • Half-life: 3-7 hours
  • Metabolism: Liver
  • Excretion: Renal
  • Mechanism of Action: Selective Beta-1 adrenergic receptor antagonist

See Also

References