Panic attack

Background

  • Can occur de novo or in setting of psychiatric disorder (most commonly panic disorder)[1]

Clinical Features

  • Discrete period of intense fear or discomfort that peaks within a few minutes 'plus at least four of the following:[1]
    • Chest pain, palpitations
    • Dyspnea, feeling of suffocation
    • Diaphoresis, hot or cold flashes
    • Nausea
    • Trembling
    • Flexor spasm of hands and feet (carpopedal spasm)
    • Paresthesias
    • Fear of death, fear of losing control
    • Depersonalization
  • May feel the "urge to flee" or "sense of impending doom"
  • The acute respiratory alkalosis can cause a transient imbalance of calcium, potassium and other ions, with the net effect of increasing the irritability of excitable muscles and nerves

Differential Diagnosis

Acute dyspnea

Emergent

Non-Emergent

Evaluation

Management

  • Reassurance and patient education
  • Consider anxiolytic (e.g. 1-2mg Lorazepam (Ativan) IV/IM/PO or 50-100mg Hydroxyzine IM)
  • Use of a brown paper bag or face mask for rebreathing has been a traditionally described treatment[2]
    • Was thought to increase the re-ventilation of expired CO2[3]
    • However, may result in morbidity and even death if erroneously applied to patients who were hypoxic or have other underlying disorder (e.g. myocardial ischemia) [4]
    • Any benefit provided is the result of the reassurance of “instructional manipulation” and patient belief in the treatment, rather than the elevated FiCO2.[5]

Disposition

  • Discharge

See Also

References

  1. 1.0 1.1 Foldes-Busque G, Denis I, Poitras J, Fleet RP, Archambault P, Dionne CE. A prospective cohort study to refine and validate the Panic Screening Score for identifying panic attacks associated with unexplained chest pain in the emergency department. BMJ Open. 2013;3(10):e003877. doi:10.1136/bmjopen-2013-003877.
  2. Hypoxic hazards of traditional paper bag rebreathing in hyperventilating patients. Annals of Emergency Medicine. June 1989. 18(6): 62-628.
  3. Hypoxic hazards of traditional paper bag rebreathing in hyperventilating patients. Annals of Emergency Medicine. June 1989. 18(6): 62-628.
  4. Hypoxic hazards of traditional paper bag rebreathing in hyperventilating patients. Annals of Emergency Medicine. June 1989. 18(6): 62-628.
  5. van den Hout MA, et al. Rebreathing to cope with hyperventilation: Experimental tests of the paper bag method. Journal of Behavioral Medicine. 1988. 11:303–310