Esmolol

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General

  • Type: Beta blockers
  • Dosage Forms:
  • Common Trade Names: Brevibloc

Adult Dosing

  • Loading dose = 500mcg/kg bolus over 1min
    • Follow this with infusion at 50mcg/kg/min for 4min
      • If no response give another 500 bolus, increased infusion to 100
      • If no response give another 500 bolus, increased infusion to 200

Pediatric Dosing

Special Populations

  • Pregnancy Rating:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug
  • Cardiogenic shock
  • 2nd or 3rd AV block

Indications

  • Supraventricular arrhythmias
  • Off label use: refractory VF

Adverse Reactions

  • Hypotension
  • Bronchospasm

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action: Class II - Short-acting Beta1 blocker
  • Onset of action = 1-4min
  • Duration of action = <30min

See Also

References