Pyloric stenosis: Difference between revisions

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==Background==
==Background==
* More common in males (5:1) & firstborn children (30%)
*More common in males (5:1) & firstborn children (30%)
* Symptoms usually begin between 3-6 weeks of age, rarely after 12 weeks  
*Symptoms usually begin between 3-6 weeks of age, rarely after 12 weeks  


==Clinical Features==
==Clinical Features==
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==Treatment==
==Treatment==
* [[IVF]]
*[[IVF]]
** Normal electrolytes and no e/o dehydration
**Normal electrolytes and no e/o dehydration
*** 5% dextrose w/ 0.25% NaCl and 2 meq KCl per 100 mL
***5% dextrose w/ 0.25% NaCl and 2 meq KCl per 100 mL
** Moderate or severe dehydration
**Moderate or severe dehydration
*** Higher NaCl concentrations (0.5% to normal saline) and higher rates of administration (1.5 to 2 times maintenance)
***Higher NaCl concentrations (0.5% to normal saline) and higher rates of administration (1.5 to 2 times maintenance)
* NGT
*NGT
* Surgery
*Surgery
** Can be delayed 24-36 hr to rehydrate infant and correct electrolytes
**Can be delayed 24-36 hr to rehydrate infant and correct electrolytes
** Ensure correction of bicarbonate level, as it may be a hypoventilation risk
**Ensure correction of bicarbonate level, as it may be a hypoventilation risk


===Precautions===
===Precautions===

Revision as of 13:57, 4 July 2016

Background

  • More common in males (5:1) & firstborn children (30%)
  • Symptoms usually begin between 3-6 weeks of age, rarely after 12 weeks

Clinical Features

  • Immediate post-prandial, non-bilious, often projectile vomiting, but desires to feed ("hungry vomiter")
  • Palpable mass in in RUQ to epigastric region, occassionally may see peristaltic waves

Differential Diagnosis

Pediatric Abdominal Pain

0–3 Months Old

3 mo–3 y old

3 y old–adolescence

Diagnosis

  • Labs may show hypokalemia, hypochloremia metabolic alkalosis
  • Imaging
    • Abdominal xray: may show large stomach bubble
    • Upper GI: string sign (narrowed pyloric sphincter)
    • U/S: thickened (>3 mm) and elongated (>15 mm) pylorus ~ 95% Sn/Sp[1]

Treatment

  • IVF
    • Normal electrolytes and no e/o dehydration
      • 5% dextrose w/ 0.25% NaCl and 2 meq KCl per 100 mL
    • Moderate or severe dehydration
      • Higher NaCl concentrations (0.5% to normal saline) and higher rates of administration (1.5 to 2 times maintenance)
  • NGT
  • Surgery
    • Can be delayed 24-36 hr to rehydrate infant and correct electrolytes
    • Ensure correction of bicarbonate level, as it may be a hypoventilation risk

Precautions

  • Ensure that kidneys are functional prior to giving potassium
  • Do not give LR
    • May lead to worsening alkalosis > apnea in infants

See Also

References

  1. Rohrschneider WK, Mittnacht H, Darge K, Tröger J. Pyloric muscle in asymptomatic infants: sonographic evaluation and discrimination from idiopathic hypertrophic pyloric stenosis. Pediatr Radiol. 1998 Jun;28(6):429-34.