Maternal vitals and labs in pregnancy

Normal Vitals in Pregnancy

Vital	Nonpregnant	1st Trimester	2nd Trimester	3rd Trimester
HR	70	78	82	85
SBP	115	112	112	114
DBP	70	60	63	70
Hcrt	40	36	33	34
WBC	7.2k	9.1k	9.7k	9.8k

Physiologic Changes in Pregnancy

• Heart rate (HR) increases 15-20 bpm (75-95 bpm)
• Mean arterial pressure (MAP) increases 10 mmHg (80 mmHg)
• Tidal volume (TV) increases 40% (700 cc)
• Minute volume (MV) increases 40% (10.5 L/min)
• Functional residual capacity (FRC) decreases 25% (1300ml)

Maternal Laboratory Changes in Pregnancy

• CBC
  • Increased WBC count (5k-15k)
  • Decreased hematocrit (32-34%) due to increased plasma volume
  • Decreased platelets
• Chemistry
  • Decreased BUN and creatinine (<0.8mg/dL)
  • GFR increases up to 60% (140ml/min)
  • Decreased Bicarb
• Other
  • Increased D-dimer and Fibrinogen
  • Increased ESR ~78
  • Decreased PaCO2 ~30
• ECG with Qs in III & aVF, left axis
• Beta-HCG Levels

See Also

• Vital signs