IV nitroglycerine alternatives
Background
- Suggestions for substitution during the IV shortage
Nitroglycerine Bioavailability
Half-life[2]: 0.05 h
Suggested Substitutions[3]
- Sublingual nitroglycerin, 1-2 tabs or sprays every 5 minutes as needed
- Once controlled
- Nitroprusside OR Isordil PO (nitro paste or longer acting NTG)
- If not well controlled
- IV enalapril 0.625-1.25mg IV bolus
- IV hydralazine 5-10mg IV bolus
- IV nitroprusside
- Once controlled
See Also
References
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