Corticosteroids

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Systemic Agents

Oral Agents

Parenteral Agents

Inhalational Agents

Topical Agents

Topical steroids, Dermatologic

Ophthalmic Steroids

  • Loteprednol ((Alrex, Lotemax)
  • Dexamethasone ophthalmic
  • Difluprednate ophthalmic (Durezol)
  • Fluorometholone
  • Prednisolone acetate (Omnipred, PredFort), prednisolone sodium phosphate
  • Rimexolone (Vexol)

Relative Strengths

Comparative Steroid Potencies[1]

Name Glucocorticoid potency Mineralocorticoid potency Duration of action (t1/2 in hours)
Cortisol (hydrocortisone) 1 1 8
Cortisone 0.8 0.8 oral 8, intramuscular 18+
Prednisone 3.5-5 0.8 16-36
Prednisolone 4 0.8 16-36
Methylprednisolone 5-7.5 0.5 18-40
Dexamethasone 25-80 0 36-54
Betamethasone 25-30 0 36-54
Triamcinolone 5 0 12-36
Beclometasone 8 puffs 4 times a day
equals 14 mg oral
prednisone once a day
- -
Fludrocortisone acetate 15 200 24
Deoxycorticosterone acetate (DOCA) 0 20 -
Aldosterone 0.3 200-1000 -

See Also

References

  1. From Liapi and Chrousos (ref. 2); Chapter 14. Glucocorticoid Therapy and Adrenal Suppression; http://www.endotext.org/adrenal/adrenal14/adrenalframe14.htm

Authors:

Ross Donaldson