Behçet's disease

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Background

Behcet's.png
  • Chronic small-vessel vasculitis
  • Mucocutaneous, ocular, cardiovascular, renal, GI, pulmonary, urologic, musculoskeletal, CNS involvement
  • Aphthous oral ulcers + ≥ 2 of following: Genital aphthae, cutaneous lesions, and neurological, oral or rheumatologic manifestations

Clinical Features

Differential Diagnosis

Evaluation

  • Clinical diagnosis
  • ESR/CRP elevated

Classification

  • International Study Group Criteria
  • Recurrent oral aphthae (at least 3 times in 1 year) + 2 of the following in absence of other systemic diseases:
    • Recurrent genital aphthae
    • Eye lesions
    • Skin lesions
    • A positive pathery test

Management

References

  • Rosen's Emergency Medicine 8th edition. 2013. Chapter: Erythematosus and the Vasculitides. p1540.
  • Smith EL, et al. Clinical manifestations and diagnosis of Behcet's disease. In: Post T, ed. UpToDate. Waltham, Mass.: UpToDate; 2014. www.uptodate.com. Accessed December 22, 2014.
  • Alnaimat FA, et al. (2014, Dec 16). Behcet Disease. eMedicine. Retrieved 12/22/2014 from http://emedicine.medscape.com/article/329099-overview