Chorea: Difference between revisions

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==Background==
==Background==
Chorea is a movement disorder characterized by involuntary worm-like movements.
*Movement disorder  
 
==Clinical Features===
*Involuntary worm-like movements


==Differential Diagnosis==
==Differential Diagnosis==
===Autoimmune===
===Autoimmune===
#Sydenham's Chorea - due to [[Acute Rheumatic Fever]]
*Sydenham's Chorea - due to [[Acute Rheumatic Fever]]
#[[Lupus]]
*[[Lupus]]
#Oral Contraceptives <ref> Miranda M, et al. Oral contraceptive induced chorea: another condition associated with anti-basal ganaglia antibodies. J Neurol Neurosurg Psychiatry 2004; 75(2): 327-328 </ref>
*Oral Contraceptives <ref> Miranda M, et al. Oral contraceptive induced chorea: another condition associated with anti-basal ganaglia antibodies. J Neurol Neurosurg Psychiatry 2004; 75(2): 327-328 </ref>
#Chorea Gravidarum - usually in 1st trimester pregnancy <ref> Bordelon YM, et al. Movement disorders in pregnancy. Semin Neurol 2007; 27(5):467-475 </ref>
*Chorea Gravidarum - usually in 1st trimester pregnancy <ref> Bordelon YM, et al. Movement disorders in pregnancy. Semin Neurol 2007; 27(5):467-475 </ref>
===Vascular===
===Vascular===
#[[Stroke]]
*[[Stroke]]
#Postpump Chorea - in children after cardiac surgery
*Postpump Chorea - in children after cardiac surgery
#Polycythemia Vera
*Polycythemia Vera
===Metabolic Disorders===
===Metabolic Disorders===
#[[Hyperosmolar Hyperglycemic State (HHS)|Nonketotic hyperglycemia]] <ref> Chang MH, et al. Non-ketotic hyperglycaemic chorea: a SPECT study. J Neurol neurosurg Psychiatry 1996; 60(4): 428-430 </ref>
*[[Hyperosmolar Hyperglycemic State (HHS)|Nonketotic hyperglycemia]] <ref> Chang MH, et al. Non-ketotic hyperglycaemic chorea: a SPECT study. J Neurol neurosurg Psychiatry 1996; 60(4): 428-430 </ref>
#[[Hyperthyroidism]] (rare)
*[[Hyperthyroidism]] (rare)
#Renal Failure
*Renal Failure
#[[Hypocalcemia]]
*[[Hypocalcemia]]
===Drugs===
===Drugs===
#Illicit Drugs
*Illicit Drugs
##[[Cocaine]]
**[[Cocaine]]
##Methamphetamines
**Methamphetamines
#Dopamine Receptor Antagonists
*Dopamine Receptor Antagonists
##Metoclopramide (Reglan)
**Metoclopramide (Reglan)
#Cimetidine
*Cimetidine
#[[Digoxin]]
*[[Digoxin]]
#[[INH|Isoniazid]]
*[[INH|Isoniazid]]
#Verapamil
*Verapamil
#Theophylline
*Theophylline
===Paraneoplastic===
===Paraneoplastic===
#Small-cell lung CA
*Small-cell lung CA


==Workup==
==Diagnosis==


==Management==
==Management==
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==See Also==
==See Also==


==Sources==
==References==
*Medscape (www.medscape.com/viewarticle/705907_6)
<references/>
<references/>


[[Category:Neuro]]
[[Category:Neuro]]

Revision as of 10:50, 2 September 2015

Background

  • Movement disorder

Clinical Features=

  • Involuntary worm-like movements

Differential Diagnosis

Autoimmune

Vascular

  • Stroke
  • Postpump Chorea - in children after cardiac surgery
  • Polycythemia Vera

Metabolic Disorders

Drugs

  • Illicit Drugs
  • Dopamine Receptor Antagonists
    • Metoclopramide (Reglan)
  • Cimetidine
  • Digoxin
  • Isoniazid
  • Verapamil
  • Theophylline

Paraneoplastic

  • Small-cell lung CA

Diagnosis

Management

Treat the underlying disorder

Disposition

  • Consult Neurology if cause is unclear

See Also

References

  1. Miranda M, et al. Oral contraceptive induced chorea: another condition associated with anti-basal ganaglia antibodies. J Neurol Neurosurg Psychiatry 2004; 75(2): 327-328
  2. Bordelon YM, et al. Movement disorders in pregnancy. Semin Neurol 2007; 27(5):467-475
  3. Chang MH, et al. Non-ketotic hyperglycaemic chorea: a SPECT study. J Neurol neurosurg Psychiatry 1996; 60(4): 428-430