Chorea

Background

  • Movement disorder

Clinical Features

  • Involuntary worm-like movements

Differential Diagnosis

Autoimmune

Vascular

  • Stroke
  • Postpump Chorea - in children after cardiac surgery
  • Polycythemia Vera

Metabolic Disorders

Drugs

  • Illicit Drugs
  • Dopamine Receptor Antagonists
    • Metoclopramide (Reglan)
  • Cimetidine
  • Digoxin
  • Isoniazid
  • Verapamil
  • Theophylline

Paraneoplastic

  • Small-cell lung CA

Evaluation

Management

Treat the underlying disorder

Disposition

  • Consult Neurology if cause is unclear

See Also

References

  1. Miranda M, et al. Oral contraceptive induced chorea: another condition associated with anti-basal ganaglia antibodies. J Neurol Neurosurg Psychiatry 2004; 75(2): 327-328
  2. Bordelon YM, et al. Movement disorders in pregnancy. Semin Neurol 2007; 27(5):467-475
  3. Chang MH, et al. Non-ketotic hyperglycaemic chorea: a SPECT study. J Neurol neurosurg Psychiatry 1996; 60(4): 428-430