Human papillomavirus

Background

• Abbreviation: HPV
• Most common STI in US.
• Associated with cervical, vulvar, penile, anal and oropharyngeal cancer.
• Vaccine available for adolescents 11 and older, and immunocompromised patients.

Clinical Features

• Most infections asymptomatic
• Anogenital warts (Condyloma acuminata)
  • painless flesh-colored papules or cauliflower-like projections
  • Contagious via skin contact
• Cervical cancer

Differential Diagnosis

Sexually transmitted diseases

• Chancroid
• Chlamydia trachomatis
• Granuloma inguinale
• Hepatitis B
• Herpes Simplex Virus-2
• HIV
• Human papillomavirus
• Lymphogranuloma venereum
• Neisseria gonorrhoeae
• Trichomonas
• Syphilis

Evaluation

• Clinical diagnosis
• Pap smear for cervical lesions

Management

• Safe-sex counseling

Disposition

Outpatient follow up

See Also

• Sexually Transmitted Diseases (STD)

References

1. CDC: HPV