Diethylcarbamazine

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Overview

Diethylcarbamazine (DEC) used as a key medication for its anti-filaricidal activity[1]

Administration

  • Mechanism of Action: interferes with cyclooxygenase and lipoxygenase pathways, reducing the production of thromboxane, prostacyclin, prostaglandin and leukotrienes
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names:

Adult Dosing

Pediatric Dosing

Special Populations

Pregnancy Rating

Lactation risk

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

Comments

See Also

References

  1. ↑ Peixoto CA et al. Anti-inflammatory effects of diethylcarbamazine: A review. European Journal of Pharmacology 734 (2014) 35–41
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