Albendazole

General

  • Type: Antiparasitic
  • Dosage Forms: 200mg
  • Common Trade Names:Albenza

Adult Dosing

  • Microsporidiosis: 400mg po bid
  • neurocysticerosis: < 60 kg: 15mg/kg/day PO BID x 8-30 days, max 800mg/day. >60 kg: 400mg PO BID x 8-30 days

Pediatric Dosing

  • neurocysticerosis: < 60 kg: 15mg/kg/day PO BID x 8-30 days, max 800mg/day. >60 kg: 400mg PO BID x 8-30 days

Special Populations

  • Pregnancy Rating:C
  • Lactation: unknown
  • Renal Dosing
    • Adult: not defined
    • Pediatric: not defined
  • Hepatic Dosing
    • Adult: not defined
    • Pediatric: not defined

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • leukopenia
  • neutropenia
  • pancytopenia
  • acute renal failure
  • hepatitis
  • SJS

Common

  • abnormal LFT's
  • abdominal pain
  • nausea/vomiting
  • headache
  • dizziness
  • alopecia
  • fever

Pharmacology

  • Half-life: 8-12 hour
  • Metabolism: liver
  • Excretion: bile
  • Mechanism of Action: inhibits tublin polymerization

See Also

References