Chloramphenicol: Difference between revisions
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==Adult Dosing== | ==Adult Dosing== | ||
===Infection, General=== | |||
*50-100 mg/kg/day IV divided q6h | |||
===Bacterial [[meningitis]]=== | |||
*4 g/day IV divided q6h | |||
*Alt: 75-100 mg/kg/day IV divided qgh | |||
==Pediatric Dosing== | ==Pediatric Dosing== | ||
Revision as of 23:09, 3 December 2015
General
- Type:
- Dosage Forms:
- Common Trade Names:
Adult Dosing
Infection, General
- 50-100 mg/kg/day IV divided q6h
Bacterial meningitis
- 4 g/day IV divided q6h
- Alt: 75-100 mg/kg/day IV divided qgh
Pediatric Dosing
Special Populations
- Pregnancy:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
Antibiotic Sensitivities[1]
Key
- S susceptible/sensitive (usually)
- I intermediate (variably susceptible/resistant)
- R resistant (or not effective clinically)
- S+ synergistic with cell wall antibiotics
- U sensitive for UTI only (non systemic infection)
- X1 no data
- X2 active in vitro, but not used clinically
- X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
- X4 active in vitro, but not clinically effective for strep pneumonia
See Also
Source
- ↑ Sanford Guide to Antimicrobial Therapy 2014