Clostridium (not difficile)

Background

Antibiotic Sensitivities[1]

Category Antibiotic Sensitivity
Penicillins Penicillin G S
Penicillin V S
Anti-Staphylocccal Penicillins Methicillin X1
Nafcillin/Oxacillin X1
Cloxacillin/Diclox. X1
Amino-Penicillins AMP/Amox S
Amox-Clav S
AMP-Sulb S
Anti-Pseudomonal Penicillins Ticarcillin S
Ticar-Clav S
Pip-Tazo S
Piperacillin S
Carbapenems Doripenem S
Ertapenem S
Imipenem S
Meropenem S
Aztreonam R
Fluroquinolones Ciprofloxacin I
Ofloxacin I
Pefloxacin X1
Levofloxacin S
Moxifloxacin I
Gemifloxacin X1
Gatifloxacin S
1st G Cephalo Cefazolin X1
2nd G. Cephalo Cefotetan S
Cefoxitin S
Cefuroxime S
3rd/4th G. Cephalo Cefotaxime S
Cefizoxime S
CefTRIAXone S
Ceftaroline X1
CefTAZidime S
Cefepime X1
Oral 1st G. Cephalo Cefadroxil X1
Cephalexin X1
Oral 2nd G. Cephalo Cefaclor/Loracarbef X1
Cefproxil S
Cefuroxime axetil S
Oral 3rd G. Cephalo Cefixime R
Ceftibuten X1
Cefpodox/Cefdinir/Cefditoren X1
Aminoglycosides Gentamicin X1
Tobramycin X1
Amikacin X1
Chloramphenicol S
Clindamycin I
Macrolides Erythromycin I
Azithromycin S
Clarithromycin S
Ketolide Telithromycin X1
Tetracyclines Doxycycline S
Minocycline S
Glycylcycline Tigecycline S
Daptomycin X1
Glyco/Lipoclycopeptides Vancomycin S
Teicoplanin S
Telavancin S
Fusidic Acid S
Trimethoprim X1
TMP-SMX X1
Urinary Agents Nitrofurantoin X1
Fosfomycin X1
Other Rifampin X1
Metronidazole S+
Quinupristin dalfoppristin X2
Linezolid X2
Colistimethate X1

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

See Also

References

  1. Sanford Guide to Antimicrobial Therapy 2014

Authors:

Ross Donaldson