Corticosteroids: Difference between revisions

 
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{| class="wikitable"
|+ Comparative steroid potencies
<ref> From Liapi and Chrousos (ref. 2); Chapter 14. Glucocorticoid Therapy and Adrenal Suppression; http://www.endotext.org/adrenal/adrenal14/adrenalframe14.htm</ref>
! Name
! Glucocorticoid potency
! Mineralocorticoid potency
! Duration of action (t<sub>1/2</sub> in hours)
|-
| [[Cortisol]] (hydrocortisone)
| 1
| 1
| 8
|-
| [[Cortisone]]
| 0.8
| 0.8
| oral 8, intramuscular 18+
|-
| [[Prednisone]]
| 3.5-5
| 0.8
| 16-36
|-
| [[Prednisolone]]
| 4
| 0.8
| 16-36
|-
| [[Methylprednisolone]]
| 5-7.5
| 0.5
| 18-40
|-
| [[Dexamethasone]]
| 25-80
| 0
| 36-54
|-
| [[Betamethasone]]
| 25-30
| 0
| 36-54
|-
| [[Triamcinolone acetonide|Triamcinolone]]
| 5
| 0
| 12-36
|-
| [[Beclometasone]]
| 8 puffs 4 times a day<br />equals 14&nbsp;mg oral<br />prednisone once a day{{clarify|date=October 2012}}
| -
| -
|-
| [[Fludrocortisone]] acetate
| 15
| 200
| 24
|-
| [[Deoxycorticosterone]] acetate (DOCA)
| 0
| 20
| -
|-
| [[Aldosterone]]
| 0.3
| 200-1000
| -
|}
==Types==
==Types==
*[[Prednisolone]]
*[[Prednisolone]]

Revision as of 23:29, 10 March 2015

Comparative steroid potencies [1]
Name Glucocorticoid potency Mineralocorticoid potency Duration of action (t1/2 in hours)
Cortisol (hydrocortisone) 1 1 8
Cortisone 0.8 0.8 oral 8, intramuscular 18+
Prednisone 3.5-5 0.8 16-36
Prednisolone 4 0.8 16-36
Methylprednisolone 5-7.5 0.5 18-40
Dexamethasone 25-80 0 36-54
Betamethasone 25-30 0 36-54
Triamcinolone 5 0 12-36
Beclometasone 8 puffs 4 times a day
equals 14 mg oral
prednisone once a day[clarification needed]
- -
Fludrocortisone acetate 15 200 24
Deoxycorticosterone acetate (DOCA) 0 20 -
Aldosterone 0.3 200-1000 -


Types

Methylprednisolone

See Also

  1. From Liapi and Chrousos (ref. 2); Chapter 14. Glucocorticoid Therapy and Adrenal Suppression; http://www.endotext.org/adrenal/adrenal14/adrenalframe14.htm