Human papillomavirus: Difference between revisions
Line 5: Line 5:
*Associated with cervical, vulvar, penile, anal and oropharyngeal cancer.
*Associated with cervical, vulvar, penile, anal and oropharyngeal cancer.
*Vaccine available for adolescents 11 and older, and immunocompromised patients.
*Vaccine available for adolescents 11 and older, and immunocompromised patients.
{| class="wikitable" style="margin:1em;"
|-
! Disease
! HPV type
|-
| Common [[wart]]s
| 2, 7, 22
|-
| [[Plantar wart]]s
| 1, 2, 4, 63
|-
| Verruca plana (Flat warts)
| 3, 10, 28
|-
| [[Anogenital warts]]
| 6, 11, 42, 44 and others<ref name=Kumar19/>
|-
| Anal dysplasia (lesions)
| 6, 16, 18, 31, 53, 58<ref>{{cite journal | vauthors = Palefsky JM, Holly EA, Ralston ML, Jay N | title = Prevalence and risk factors for human papillomavirus infection of the anal canal in human immunodeficiency virus (HIV)-positive and HIV-negative homosexual men | journal = The Journal of Infectious Diseases | volume = 177 | issue = 2 | pages = 361–7 | date = February 1998 | pmid = 9466522 | doi = 10.1086/514194 }}</ref>
|-
| Genital cancers
|
*Highest risk: 16, 18, 31, 45
*Other high-risk: 33, 35, 39, 51, 52, 56, 58, 59
*Probably high-risk: 26, 53, 66, 68, 73, 82
|-
| Epidermodysplasia verruciformis
| more than 15 types
|-
| Focal epithelial hyperplasia (mouth)
| 13, 32
|-
| Mouth [[papillomas]]
| 6, 7, 11, 16, 32
|-
| Oropharyngeal cancer
| 16
|-
| [[Verrucous cyst]]
| 60
|-
| Laryngeal papillomatosis
| 6, 11
|}


==Clinical Features==
==Clinical Features==

Revision as of 19:22, 10 September 2020

Background

  • Abbreviation: HPV
  • Most common STI in US.
  • Over 200 HPV types, with 40 that infect the genital mucosa [1]
  • Associated with cervical, vulvar, penile, anal and oropharyngeal cancer.
  • Vaccine available for adolescents 11 and older, and immunocompromised patients.


Disease HPV type
Common warts 2, 7, 22
Plantar warts 1, 2, 4, 63
Verruca plana (Flat warts) 3, 10, 28
Anogenital warts 6, 11, 42, 44 and others[2]
Anal dysplasia (lesions) 6, 16, 18, 31, 53, 58[3]
Genital cancers
  • Highest risk: 16, 18, 31, 45
  • Other high-risk: 33, 35, 39, 51, 52, 56, 58, 59
  • Probably high-risk: 26, 53, 66, 68, 73, 82
Epidermodysplasia verruciformis more than 15 types
Focal epithelial hyperplasia (mouth) 13, 32
Mouth papillomas 6, 7, 11, 16, 32
Oropharyngeal cancer 16
Verrucous cyst 60
Laryngeal papillomatosis 6, 11

Clinical Features

  • Most infections asymptomatic
  • Anogenital warts (Condyloma acuminata)
    • painless flesh-colored papules or cauliflower-like projections
    • Contagious via skin contact
  • Cervical cancer

Differential Diagnosis

Sexually transmitted diseases

Evaluation

  • Clinical diagnosis
  • Pap smear for cervical lesions

Management

  • Safe-sex counseling (HPV-2)

Disposition

Outpatient follow up

See Also

External Links

References

1. CDC: HPV

  1. ↑ Cdc.gov. (2018). Surveillance Manual | HPV | Vaccine Preventable Diseases | CDC. [online] Available at: https://www.cdc.gov/vaccines/pubs/surv-manual/chpt05-hpv.html [Accessed 3 May 2018].
  2. ↑ Cite error: Invalid <ref> tag; no text was provided for refs named Kumar19
  3. ↑ Template:Cite journal
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