Aminoglycosides: Difference between revisions

Revision as of 23:45, 26 December 2016

Used (alone or with beta-lactam) to treat serious infections due to gram-negative bacilli, e.g.:
- Ill patient with pyelonephritis
- Meningitis (due to pseudomonas, acinetobacter)
- Peritoneal dialysis-associated peritonitis
- Bacterial endocarditis
Used +/- beta-lactam
Can precipitate crisis in patients with myasthenia gravis

Goodman & Gilman's Pharmacology

Authors:

@@ Line 1: / Line 1: @@
-*Gentamicin, [[amikacin]], streptomycin (either alone or with B-lactam)
+==Background==
-**Serious gram-negative bacillary infections
+*Used (alone or with beta-lactam) to treat serious infections due to [[gram-negative bacilli]], e.g.:
-***Ill patient with pyelonephritis
+**Ill patient with [[pyelonephritis]]
-***Meningitis (due to Pseudomonas, Acinetobacter)
+**[[Meningitis]] (due to [[pseudomonas]], [[acinetobacter]])
-***Peritoneal Dialysis–Associated Peritonitis
+**[[Peritoneal dialysis-associated peritonitis]]
-***Bacterial endocarditis?
+**Bacterial [[endocarditis]]
-*Caution: Use in patients with Myasthenia Gravis, can precipitate crisis
+*Used +/- [[beta-lactam]]
+*Can precipitate crisis in patients with [[myasthenia gravis]]
+==Specific Aminoglycosides==
+*[[Gentamycin]]
+*[[Streptomycin]]
+*[[Neomycin]]
+*[[Amikacin]]
+*[[Kanamycin]]
+*[[Tobramycin]]
 ==See Also==