Pulmonary edema: Difference between revisions

Line 12: Line 12:
#CPAP/BiPAP with PEEP 6-8; titrate up to PEEP of 10-12
#CPAP/BiPAP with PEEP 6-8; titrate up to PEEP of 10-12
#Nitroglycerin
#Nitroglycerin
##Dosing Options
#*Dosing Options
###Sublingual 0.4 mg q5min
#**Sublingual 0.4 mg q5min
###Nitropaste (better bioavailability than oral Nitroglycerin)
#**Nitropaste (better bioavailability than oral Nitroglycerin)
###Intravenous: 0.1mcg/kg/min - 5mcg/kg/min  
#**Intravenous: 0.1mcg/kg/min - 5mcg/kg/min  


''Generally start IV Nitroglycerin 50mcg/min and titrate rapidly (150mcg/min or higher)to symptom relief''
''Generally start IV Nitroglycerin 50mcg/min and titrate rapidly (150mcg/min or higher)to symptom relief''

Revision as of 14:24, 1 June 2015

Background

Pulmonary Edema Types

Pulmonary capillary wedge pressure <18 mmHg differentiates noncardiogenic from cardiogenic pulmonary edema[1]

Diagnosis

  • Crackles
  • Respiratory distress

Differential Diagnosis

Acute dyspnea

Emergent

Non-Emergent

Treatment

  1. CPAP/BiPAP with PEEP 6-8; titrate up to PEEP of 10-12
  2. Nitroglycerin
    • Dosing Options
      • Sublingual 0.4 mg q5min
      • Nitropaste (better bioavailability than oral Nitroglycerin)
      • Intravenous: 0.1mcg/kg/min - 5mcg/kg/min

Generally start IV Nitroglycerin 50mcg/min and titrate rapidly (150mcg/min or higher)to symptom relief

  • If NTG fails to reduce BP consider nitroprusside (reduces both preload and afterload) or ACE-inhibitiors (preload reducer)
  • After pt improves titrate down NTG as enaliprilat (0.625 - 1.25mg IV) or captopril are started
  • Morphine is no longer recommended do to increased morbidity

See Also

References

  1. Clark SB, Soos MP. Noncardiogenic Pulmonary Edema. In: StatPearls. Treasure Island (FL): StatPearls Publishing; October 1, 2020.