Pulmonary edema: Difference between revisions

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==Background==
==Background==
*Cardiogenic vs Non-Cardiogenic (ARDS/Altitude/Neurogenic)
===Causes===
*Mechanism of Cardiogenic
**Failing heart > pulm edema > stress response > incr afterload
***Incr afterload > incr pulm edema
*Pts often intravascularly depleted; avoid diuretics!
 
==Causes==
*[[Congestive heart failure|Cardiogenic]]
*[[Congestive heart failure|Cardiogenic]]
*Non-cardiogenic
*Non-cardiogenic
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*Other
*Other
**[[ARDS]]
**[[ARDS]]
**Inhalation of hot or toxic gases
**Inhalation injury
**[[Pulmonary contusion]]
**[[Pulmonary contusion]]
**Aspiration
**Aspiration
**Reexpansion edema (post large volume thoracocentesis, resolution of pneumothorax, post decortication, removal of endobronchial obstruction, effectively a form of negative pressure pulmonary oedema.
**Reexpansion edema (post large volume thoracocentesis, resolution of pneumothorax, post decortication, removal of endobronchial obstruction, effectively a form of negative pressure pulmonary oedema.
Reperfusion injury, i.e. postpulmonary thromboendartectomy or lung transplantation
*Reperfusion injury, i.e. postpulmonary thromboendartectomy or lung transplantation
Immersion pulmonary edema[7][8]
*Immersion pulmonary edema[7][8]
Multiple blood transfusions
*Iatrogenic fluid overload
Severe infection or inflammation which may be local or systemic. This is the classical form of ALI-ARDS.
**Multiple blood transfusions
There are also a range of causes of pulmonary edema which are less well characterised and arguably represent specific instances of the broader classifications above.
**IV fluid
 
*Hantavirus pulmonary syndrome
Arteriovenous malformation
*[[High altitude pulmonary edema]]
Hantavirus pulmonary syndrome
High altitude pulmonary edema (HAPE), probably a manifestation of neurogenic pulmonary edema[9][10]
Envenomation, such as with the venom of Atrax robustus[11]
Envenomation, such as with the venom of Atrax robustus[11]
Flash pulmonary edema
Swimming induced pulmonary edema


==Diagnosis==
==Diagnosis==

Revision as of 20:52, 24 March 2015

Background

Causes

Envenomation, such as with the venom of Atrax robustus[11]

Diagnosis

  • Crackles
  • Respiratory distress

Differential Diagnosis

Acute dyspnea

Emergent

Non-Emergent

Treatment

  1. CPAP/BiPAP with PEEP 6-8; titrate up to PEEP of 10-12
  2. Nitroglycerin
    1. Dosing Options
      1. Sublingual 0.4 mg q5min
      2. Nitropaste (better bioavailability than oral Nitroglycerin)
      3. Intravenous: 0.1mcg/kg/min - 5mcg/kg/min

Generally start IV Nitroglycerin 50mcg/min and titrate rapidly (150mcg/min or higher)to symptom relief

  • If NTG fails to reduce BP consider nitroprusside (reduces both preload and afterload) or ACE-inhibitiors (preload reducer)
  • After pt improves titrate down NTG as enaliprilat (0.625 - 1.25mg IV) or captopril are started
  • Morphine is no longer recommended do to increased morbidity

See Also

References