Corticosteroids: Difference between revisions

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{| class="wikitable"
==Systemic Agents==
|+ Comparative steroid potencies
===Oral Agents===
<ref> From Liapi and Chrousos (ref. 2); Chapter 14. Glucocorticoid Therapy and Adrenal Suppression; http://www.endotext.org/adrenal/adrenal14/adrenalframe14.htm</ref>
! Name
! Glucocorticoid potency
! Mineralocorticoid potency
! Duration of action (t<sub>1/2</sub> in hours)
|-
| [[Cortisol]] (hydrocortisone)
| 1
| 1
| 8
|-
| [[Cortisone]]
| 0.8
| 0.8
| oral 8, intramuscular 18+
|-
| [[Prednisone]]
| 3.5-5
| 0.8
| 16-36
|-
| [[Prednisolone]]
| 4
| 0.8
| 16-36
|-
| [[Methylprednisolone]]
| 5-7.5
| 0.5
| 18-40
|-
| [[Dexamethasone]]
| 25-80
| 0
| 36-54
|-
| [[Betamethasone]]
| 25-30
| 0
| 36-54
|-
| [[Triamcinolone acetonide|Triamcinolone]]
| 5
| 0
| 12-36
|-
| [[Beclometasone]]
| 8 puffs 4 times a day<br />equals 14&nbsp;mg oral<br />prednisone once a day{{clarify|date=October 2012}}
| -
| -
|-
| [[Fludrocortisone]] acetate
| 15
| 200
| 24
|-
| [[Deoxycorticosterone]] acetate (DOCA)
| 0
| 20
| -
|-
| [[Aldosterone]]
| 0.3
| 200-1000
| -
|}
 
 
==Types==
*[[Prednisolone]]
*[[Prednisolone]]
*[[Prednisone]]
*[[Prednisone]]
[[Methylprednisolone]]
*[[Dexamethasone]]
*[[Dexamethasone]]
*[[Fludrocortisone]]
*[[Cortisone]], [[Hydrocortisone]]
===Parenteral Agents===
*[[Methylprednisolone]]
*[[Dexamethasone]]
*[[Cortisone]], [[Hydrocortisone]]
*[[Betamethasone]] Sodium Phosphate/Betamethasone Acetate
==Inhalational Agents==
*[[Flunisolide]]
*[[Fluticasone furoate]], [[Fluticasone propionate]]
*[[Triamcinolone acetonide]]
*[[Beclomethasone]]
*[[Budesonide]] (Pulmicort)
*[[Ciclesonide]]
*[[Mometasone]] (Nasonex)
*Combination inhalers
**[[Azelastine hydrochloride]]/[[Fluticasone propionate]]*[[Fluticasone propionate]]/[[salmeterol]] xinafoate
**[[Budesonide/Formoterol]]
**[[Mometasone furoate/Formoterol fumarate]]
==Topical Agents==
===[[Topical steroids]], Dermatologic===
*[[Clobetasol]]
*[[Betamethasone]]
*[[Halobetasol]]
*[[Diflorasone diacetate]]
*[[Fluocinonide]]
*[[Halcinonide]]
*[[Amcinonide]]
*[[Desoximetasone]]
*[[Triamcinolone]]
*[[Mometasone]]
*[[Fluticasone]]
*[[Halometasone]]
*[[Fluocinolone]]
*[[Hydrocortisone]]
*[[Flurandrenolide]]
*[[Desonide]]
*[[Alclometasone]]
===Ophthalmic Steroids===
*[[Loteprednol]] ((Alrex, Lotemax)
*[[Dexamethasone]] ophthalmic
*Difluprednate ophthalmic (Durezol)
*Fluorometholone
*[[Prednisolone]] acetate (Omnipred, PredFort), prednisolone sodium phosphate
*Rimexolone (Vexol)
==Relative Strengths==
{{Relative steroid strengths table}}


==See Also==
==See Also==
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*[[Inhaled steroids]]
*[[Inhaled steroids]]


[[Category:Drugs]]
==References==
<references/>
 
[[Category:Pharmacology]]

Latest revision as of 17:59, 20 September 2019

Systemic Agents

Oral Agents

Parenteral Agents

Inhalational Agents

Topical Agents

Topical steroids, Dermatologic

Ophthalmic Steroids

  • Loteprednol ((Alrex, Lotemax)
  • Dexamethasone ophthalmic
  • Difluprednate ophthalmic (Durezol)
  • Fluorometholone
  • Prednisolone acetate (Omnipred, PredFort), prednisolone sodium phosphate
  • Rimexolone (Vexol)

Relative Strengths

Comparative Steroid Potencies[1]

Name Glucocorticoid potency Mineralocorticoid potency Duration of action (t1/2 in hours)
Cortisol (hydrocortisone) 1 1 8
Cortisone 0.8 0.8 oral 8, intramuscular 18+
Prednisone 3.5-5 0.8 16-36
Prednisolone 4 0.8 16-36
Methylprednisolone 5-7.5 0.5 18-40
Dexamethasone 25-80 0 36-54
Betamethasone 25-30 0 36-54
Triamcinolone 5 0 12-36
Beclometasone 8 puffs 4 times a day
equals 14 mg oral
prednisone once a day
- -
Fludrocortisone acetate 15 200 24
Deoxycorticosterone acetate (DOCA) 0 20 -
Aldosterone 0.3 200-1000 -

See Also

References

  1. From Liapi and Chrousos (ref. 2); Chapter 14. Glucocorticoid Therapy and Adrenal Suppression; http://www.endotext.org/adrenal/adrenal14/adrenalframe14.htm