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{{#ask: [[Is DrugClass::Benzodiazepine]] | ?SeizureDose=Dose | ?BrandName=Trade Name}}


{| class="wikitable unsortable center" style="margin: 1em auto;"
[[Scarlet_fever_1.2.jpg|thumb|"Slapped cheeks" and "white mustache" (circumoral pallor) typical of scarlet fever.]]
|+ Overdose symptoms by system
! scope="col" style="text-align:center"| System
! scope="col" style="width: 40%;"| Minor or moderate overdose<ref name="FDA Abuse & OD" /><ref name="Westfall" /><ref name="International" />
! scope="col" style="width: 50%;"| Severe overdose{{#tag:ref|<ref name="Acute amph toxicity">{{cite journal |vauthors=Greene SL, Kerr F, Braitberg G | title = Review article: amphetamines and related drugs of abuse | journal = Emerg. Med. Australas. | volume = 20 | issue = 5 | pages = 391–402 | date = October 2008 | pmid = 18973636 | doi = 10.1111/j.1742-6723.2008.01114.x }}</ref><ref name="FDA Abuse & OD" /><ref name="Westfall" /><ref name="Amphetamine toxidrome" /><ref name="Albertson_2011">{{cite book|veditors=Olson KR, Anderson IB, Benowitz NL, Blanc PD, Kearney TE, Kim-Katz SY, Wu AH | title = Poisoning & Drug Overdose | author = Albertson TE| year = 2011 | publisher = McGraw-Hill Medical | location = New York | isbn = 9780071668330 | chapter = Amphetamines | pages = 77–79 | edition = 6th }}</ref>| group = "sources"}}
|-
! scope="row"| [[Cardiovascular system|Cardiovascular]]
|
* [[Cardiac dysrhythmia|Abnormal heartbeat]]
* [[Hypertension|High]] or [[Hypotension|low blood pressure]]
|
* [[Cardiogenic shock]] (heart not pumping enough blood)
* [[Cerebral hemorrhage]] (bleeding in the brain)
* [[Circulatory collapse]] (partial or complete failure of the [[circulatory system]])
|-
! scope="row"| [[Central nervous system|Central nervous<br />system]]
|
* Confusion
* [[Hyperreflexia|Abnormally fast reflexes]]
* Severe agitation
* [[Tremor]] (involuntary muscle twitching)
|
* [[Stimulant psychosis#Substituted amphetamines|Acute amphetamine psychosis]] (e.g., [[delusion]]s and [[paranoia]])
* [[Stereotypy|Compulsive and repetitive movement]]
* [[Serotonin syndrome]] (excessive serotonergic nerve activity)
* [[Sympathomimetic toxidrome]] (excessive adrenergic nerve activity)
|-
! scope="row"| [[Musculoskeletal system|Musculoskeletal]]
|
* [[Myalgia|Muscle pain]]
|
* [[Rhabdomyolysis]] (rapid muscle breakdown)
|-
! scope="row"| [[Respiratory system|Respiratory]]
|
* Rapid breathing
|
* [[Pulmonary edema]] (fluid accumulation in the lungs)
* [[Pulmonary hypertension]] (high blood pressure in the [[Pulmonary artery|arteries of the lung]])
* [[Respiratory alkalosis]] (reduced blood [[carbon dioxide|CO<sub>2</sub>]])
|-
! scope="row"| [[Urogenital system|Urinary]]
|
* [[Dysuria|Painful urination]]
* [[Urinary retention]] (inability to urinate)
|
* [[Anuria|No urine production]]
* [[Kidney failure]]
|-
! scope="row"| Other
|
* [[Hyperthermia|Elevated body temperature]]
* [[Mydriasis]] (dilated pupils)
|
* [[Hyperkalemia|Elevated]] or [[Hypokalemia|low blood potassium]]
* [[Hyperpyrexia]] (extremely elevated [[core body temperature]])
* [[Metabolic acidosis]] (excessively acidic bodily fluids)
|}

Latest revision as of 19:21, 5 November 2025