IV nitroglycerine alternatives: Difference between revisions

Latest revision as of 20:51, 22 September 2019

Half-life^[2]: 0.05 h

Authors:

@@ Line 2: / Line 2: @@
 *Suggestions for substitution during the IV shortage
-==Suggested Substitution<ref>http://www.medpagetoday.com/EmergencyMedicine/EmergencyMedicine/45056</ref>==
+===[[Nitroglycerine]] Bioavailability===
-#Sublingual nitroglycerin, 1-2 tabs or sprays every 5 minutes as needed
+*Oral <ref name="availability">http://sepia.unil.ch/pharmacology/index.php?id=51</ref>:     <1%
-##Once controlled, transition to NTP or isordil PO (nitro paste or longer acting NTG)
+*Sublingual <ref name="availability"/>: 38% (15-40%)
-##If not well controlled
+*Topical <ref name="availability" />: 72%
-##IV enalapril 0.625-1.25mg IV bolus
-##IV hydralazine 5-10mg IV bolus
-##IV nitropursside
-==Source==
+Half-life<ref>http://sepia.unil.ch/pharmacology/index.php?id=60</ref>: 0.05 h
+==Suggested Substitutions<ref>http://www.medpagetoday.com/EmergencyMedicine/EmergencyMedicine/45056</ref>==
+*Sublingual nitroglycerin, 1-2 tabs or sprays every 5 minutes as needed
+**Once controlled
+***[[Nitroprusside]] '''OR''' [[Isordil]] PO (nitro paste or longer acting NTG)
+**If not well controlled
+***IV [[enalapril]] 0.625-1.25mg IV bolus
+***IV [[hydralazine]] 5-10mg IV bolus
+***IV [[nitroprusside]]
+==See Also==
+*[[Hypertensive emergency]]
+*[[Congestive heart failure]]
+==References==
 <references>
+[[Category:Pharmacology]]
+[[Category:Cardiology]]