|
|
| Line 1: |
Line 1: |
| ==Lidocaine== | | ==[[Lidocaine]]== |
| === Adult Dosing ===
| |
| | |
| *Loading dose = 1-1.5 mg/kg
| |
| **Additional boluses of 0.5-0.75 mg/kg q5-10min up to max of 3mg/kg
| |
| **If effective start infusion of 2mg/min
| |
| | |
| === Contraindications ===
| |
| | |
| *High SA or AV block
| |
| | |
| === Indications ===
| |
| | |
| *Treatment of ventricular arrhythmias and ectopy
| |
| **Considered 2nd-line to amiodarone for tx of V-fib and pulseless v-tach
| |
| | |
| === Mechanism of Action ===
| |
| | |
| *Class Ib
| |
| **Binds to fast Na channels in inactive state thereby inhibiting recovery after repolarization
| |
| **Acts preferentially on ischemic tissue
| |
| ***Elevates V-fib threshold
| |
| ***Suppresses ventricular ectopy
| |
| *Little effect on vascular tone, contractility or cardiac output
| |
| | |
| === Adverse Drug Rxns ===
| |
| | |
| *CNS
| |
| **Abrupt change in MS, drowsiness, confusion, sz
| |
| | |
| === Kinetics ===
| |
| | |
| *Onset of action = 45-90s
| |
| *Duration of action = 10-20min
| |
|
| |
|
| == [[Procainamide]] == | | == [[Procainamide]] == |
