Graft-vs-host disease: Difference between revisions
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==See Also== | ==See Also== | ||
*[[Transplant complications]] | |||
{{Transfusion reactions see also}} | {{Transfusion reactions see also}} | ||
Revision as of 20:20, 4 February 2016
Background
- Acute vs Chronic
- Acute: 1-12 weeks post graft (<100 days)
- Chronic: >12 weeks
- Transplanted graft with immunologically competent cells stimulated by host antigens and host is incapable of mounting an effective immunologic response
- Occurs in leukemia/lymphoma or immunocompromised
- Most commonly post HSCT: Hematopoietic stem cell transplant
- Rare in solid organ transplant
Clinical Features
Differential Diagnosis
Transfusion Reaction Types
- Acute
- Delayed
Diagnosis
- LFT abnormalities
- Pancytopenia
Management
- Glucocorticoids
Disposition
See Also
- Transplant complications
- Transfusions
- Acute transfusion reaction
- Extravascular hemolytic tranfusion reaction
- Graft-vs-host disease