Central nervous system tumor (peds): Difference between revisions

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*2nd most common pediatric cancer (20%)  
*2nd most common pediatric cancer (20%)  


==Diagnosis==
==Clinical Features==
*Depends on location
*Depends on location
**Posterior Fossa
**Posterior Fossa
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***Visual changes, hypothalamic dysfunction (DI, stunted growth, hypothyroidism)
***Visual changes, hypothalamic dysfunction (DI, stunted growth, hypothyroidism)


==Work-Up==
==Differential Diagnosis==
[[Head CT]]
 
==Diagnosis==
*[[Head CT]]


==Treatment==
==Treatment==
*Increased ICP
*[[Increased ICP]]
**Phenytoin if actively seizing
**Phenytoin if actively seizing
**Dexamethsone 1mg/yr of age (max 10mg)
**Dexamethsone 1mg/yr of age (max 10mg)
***Do NOT give if CNS lymphoma is in the ddx
***Do NOT give if CNS lymphoma is in the differential


==See Also==
==See Also==
[[Herniation Syndromes]]
*[[Herniation Syndromes]]


==Source==
==References==
Tintinalli


[[Category:Heme/Onc]]
[[Category:Heme/Onc]]
[[Category:Neuro]]
[[Category:Neuro]]
[[Category:Peds]]
[[Category:Peds]]

Revision as of 06:49, 6 June 2015

Background

  • 2nd most common pediatric cancer (20%)

Clinical Features

  • Depends on location
    • Posterior Fossa
      • Headache
        • Early morning (sleep > hypoventilation > hypercarbia > incr CNS bloodflow > incr ICP)
      • Effortless vomiting
      • CN palsies (esp 6th nerve)
    • Brainstem
      • CN deficits (facial weakness, abducens palsy, dysphagia), ataxia
    • Supratentorial
      • HA, personality change, motor weakness, Sz
    • Sellar
      • Visual changes, hypothalamic dysfunction (DI, stunted growth, hypothyroidism)

Differential Diagnosis

Diagnosis

Treatment

  • Increased ICP
    • Phenytoin if actively seizing
    • Dexamethsone 1mg/yr of age (max 10mg)
      • Do NOT give if CNS lymphoma is in the differential

See Also

References