Central nervous system tumor (peds)

This page is for pediatric patients. For adult patients, see: Central nervous system tumor.


  • 2nd most common pediatric cancer (20%)

Clinical Features

Differential Diagnosis

Pediatric Headache


Giant parietal lobe infantile gliosarcoma in a 5-year-old child.
Pediatric choroid plexus carcinoma.


  • Increased ICP
    • Benzodiazepines +/- AEDs if actively seizing
    • Dexamethasone(reduce tumor capillary permeability, inflammatory cytotoxicity)- 1mg/yr of age (max 10mg)
      • Do NOT give if CNS lymphoma is in the differential
    • Elevate head of bed to 30 degrees, provide adequate sedation in intubated patients
    • Maintain cerebral perfusion (euvolemia, vasopressors if necessary)
    • Consider osmotherapy (e.g. hypertonic saline, mannitol)

See Also