Anaerobic bacteria

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Background

  • Origin - gut, mouth, head/neck (50% of chronic sinusitis), lung, female gu tract
  • Cant grow unless culture specifically asked. 3% of bacteremia, <1% of cystitis

Organisms

  • Bacteroides (GNR)
  • Peptostreptococus (GPC)
  • P. Acnes (GPR)
  • Clostridium (GPR)

Anerobic Antibiogram

Category Organism Actinomyces Bacteroides fragilis Prevotella melaninogenica Clostridium difficile Clostridium (not difficile) Fusobacterium necrophorum Peptostreptococcus sp.
Penicillins Penicillin G S R S X2 S I S
Penicillin V I I R X1 S I S
Anti-Staphylocccal Penicillins Methicillin R R R X1 X1 X1 S
Nafcillin/Oxacillin R R R X1 X1 X1 S
Cloxacillin/Diclox. R R R X1 X1 X1 S
Amino-Penicillins AMP/Amox S R S X1 S S S
Amox-Clav S S S X1 S S S
AMP-Sulb S S S X2 S S S
Anti-Pseudomonal Penicillins Ticarcillin X1 R S X1 S X1 S
Ticar-Clav X1 S S X1 S S S
Pip-Tazo X1 S S X1 S S S
Piperacillin S R S X2 S X1 S
Carbapenems Doripenem X1 S S X2 S S S
Ertapenem S S S X2 S S S
Imipenem S S S X2 S S S
Meropenem X1 S S X2 S S S
Aztreonam R R R R R X1 R
Fluroquinolones Ciprofloxacin R R R R I X1 I
Ofloxacin I R I X1 I X1 I
Pefloxacin X1 R X1 X1 X1 X1 X1
Levofloxacin X1 R S R S X1 S
Moxifloxacin S I S R I I S
Gemifloxacin X1 R X1 X1 X1 X1 X1
Gatifloxacin S I S R S X1 S
1st G Cephalo Cefazolin X1 R X1 X1 X1 X1 X1
2nd G. Cephalo Cefotetan X1 I S X1 S X1 S
Cefoxitin X1 S S R S S S
Cefuroxime X1 R S X1 S X1 S
3rd/4th G. Cephalo Cefotaxime X1 R S R S X1 S
Cefizoxime S I S R S X1 S
CefTRIAXone S R I X1 S X1 S
Ceftaroline X1 R X1 X1 X1 X1 X1
CefTAZidime X1 R S X1 S X1 S
Cefepime X1 R R R X1 X1 S
Oral 1st G. Cephalo Cefadroxil X1 X1 X1 X1 X1 X1 X1
Cephalexin X1 R X1 X1 X1 X1 S
Oral 2nd G. Cephalo Cefaclor/Loracarbef X1 R S X1 X1 X1 S
Cefproxil X1 R S X1 S X1 S
Cefuroxime axetil X1 R S X1 S X1 S
Oral 3rd G. Cephalo Cefixime X1 R S X1 R X1 S
Ceftibuten X1 R X1 X1 X1 X1 X1
Cefpodox/Cefdinir/Cefditoren X1 X1 X1 X1 X1 X1 X1
Aminoglycosides Gentamicin R R R R X1 R R
Tobramycin R R R R X1 R R
Amikacin R R R R X1 R R
Chloramphenicol X2 X2 S I S S S
Clindamycin S I S X1 I S S
Macrolides Erythromycin S R X1 X1 I R I
Azithromycin S R S X1 S R S
Clarithromycin S R S X1 S R I
Ketolide Telithromycin X1 X1 X1 X1 X1 X1 S
Tetracyclines Doxycycline S I S X1 S X1 S
Minocycline S I S X1 S X1 S
Glycylcycline Tigecycline X1 S S X1 S S S
Daptomycin X1 X1 X1 X1 X1 X1 X1
Glyco/Lipoclycopeptides Vancomycin S R R S S X1 S
Teicoplanin X1 X1 X1 S S X1 S
Telavancin S R R S S X1 S
Fusidic Acid S X1 S X1 S X1 S
Trimethoprim X1 X2 X1 X1 X1 X1 X1
TMP-SMX X1 R X1 X1 X1 X1 X1
Urinary Agents Nitrofurantoin X1 X1 X1 X1 X1 X1 X1
Fosfomycin X1 X1 X1 X1 X1 X1 X1
Other Rifampin X1 X1 X1 X1 X1 X1 X1
Metronidazole R S S S S+ S I
Quinupristin dalfoppristin X1 X1 S I X2 X1 X1
Linezolid X1 I X1 I X2 X1 S
Colistimethate X1 X1 X1 X1 X1 X1 X1

Table Overview

See Also

References

Authors

Michael Holtz