Anthrax: Difference between revisions

Revision as of 13:52, 15 March 2011

Background

Gm positive rod, tough spores
Inhalational Anthrax: Russian accident at Sverdlovsk
Incubation Period is 10 days
No one < 24 died

Ddx

Cutaneous (painless)
1. Ecthyma gangrenosum
2. Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)
3. Ulceroglandular tularemia
4. Plague
5. Glanders (Pseudomonas peudomallei)
6. Rickettsialpox (Rickettsia akari)
7. Orf (parapox virus)
8. Staph lymphadenitis
9. TB
10. Leprosy
11. Buruli ulcer (Mycobact ulcerans)
Inhalational
1. Acute bacterial mediastinitis
2. Mycoplasma
3. Legionnaire's
4. Psittacosis
5. Tularemia
6. Q fever (Coxiella burnetti)
7. Viral pneumonia
8. Histoplasmosis
9. Coccidiomycosis
10. Ruptured aortic aneurysm
11. SVC syndrome
12. Silicosis
13. Sarcoidosis

Imaging

CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis

Treatment

Cipro 500 mg bid or 30 mg/kg div q12
Levo 500 mg qd
Doxycycline 100 mg bid
x 60 days

PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks

Source

7/2/09 PANI

Authors:

@@ Line 1: / Line 1: @@
 ==Background ==
+#Gm positive rod, tough spores
+#Inhalational Anthrax: Russian accident at Sverdlovsk
-Gm positive rod, tough spores
+#Incubation Period is 10 days
+#No one < 24 died
-Inhalational Anthrax: Russian accident at Sverdlovsk
--Incubation Period is 10 days
--No one < 24 died
 ==Ddx==
+#Cutaneous (painless)
+##Ecthyma gangrenosum
-Cutaneous (painless):
+##Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)
+##Ulceroglandular tularemia
--Ecthyma gangrenosum
+##Plague
+##Glanders (Pseudomonas peudomallei)
--Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)
+##Rickettsialpox (Rickettsia akari)
+##Orf (parapox virus)
--Ulceroglandular tularemia
+##Staph lymphadenitis
+##TB
--Plague
+##Leprosy
+##Buruli ulcer (Mycobact ulcerans)
--Glanders (Pseudomonas peudomallei)
+#Inhalational
+##Acute bacterial mediastinitis
--Rickettsialpox (Rickettsia akari)
+##Mycoplasma
+##Legionnaire's
--Orf (parapox virus)
+##Psittacosis
+##Tularemia
--Staph lymphadenitis
+##Q fever (Coxiella burnetti)
+##Viral pneumonia
--TB
+##Histoplasmosis
+##Coccidiomycosis
--Leprosy
+##Ruptured aortic aneurysm
+##SVC syndrome
--Buruli ulcer (Mycobact ulcerans)
+##Silicosis
+##Sarcoidosis
-Inhalational:
--Acute bacterial mediastinitis
--Mycoplasma
--Legionnaire's
--Psittacosis
--Tularemia
--Q fever (Coxiella burnetti)
--Viral pneumonia
--Histoplasmosis
--Coccidiomycosis
--Ruptured aortic aneurysm
--SVC syndrome
--Silicosis
--Sarcoidosis
 ==Imaging==
 CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis
 ==Treatment==
+#Cipro 500 mg bid or 30 mg/kg div q12
+#Levo 500 mg qd
-Cipro 500 mg bid or 30 mg/kg div q12
+#Doxycycline 100 mg bid
+#x 60 days
-Levo 500 mg qd
-Doxycycline 100 mg bid
-x 60 days
 PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks
 ==Source ==
 /2/09 PANI
 [[Category:ID]]