Anthrax: Difference between revisions

Revision as of 22:08, 29 October 2010

Background

Gm positive rod, tough spores Inhalational Anthrax: Russian accident at Sverdlovsk -Incubation Period is 10 days -No one < 24 died

Ddx

Cutaneous (painless): -Ecthyma gangrenosum -Rat-bite fever (Streptobacillus monilifomis and Spirillum minus) -Ulceroglandular tularemia -Plague -Glanders (Pseudomonas peudomallei) -Rickettsialpox (Rickettsia akari) -Orf (parapox virus) -Staph lymphadenitis -TB -Leprosy -Buruli ulcer (Mycobact ulcerans)

Inhalational: -Acute bacterial mediastinitis -Mycoplasma -Legionnaire's -Psittacosis -Tularemia -Q fever (Coxiella burnetti) -Viral pneumonia -Histoplasmosis -Coccidiomycosis -Ruptured aortic aneurysm -SVC syndrome -Silicosis -Sarcoidosis

Imaging

CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis

Treatment

Cipro 500 mg bid or 30 mg/kg div q12 Levo 500 mg qd Doxycycline 100 mg bid x 60 days

PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks

Source

7/2/09 PANI

Authors:

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-==Background ==Gm positive rod, tough sporesInhalational Anthrax: Russian accident at Sverdlovsk-Incubation Period is 10 days-No one < 24 died ==Ddx==Cutaneous (painless):-Ecthyma gangrenosum-Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)-Ulceroglandular tularemia-Plague-Glanders (Pseudomonas peudomallei)-Rickettsialpox (Rickettsia akari)-Orf (parapox virus)-Staph lymphadenitis-TB-Leprosy-Buruli ulcer (Mycobact ulcerans) Inhalational:-Acute bacterial mediastinitis-Mycoplasma-Legionnaire's-Psittacosis-Tularemia-Q fever (Coxiella burnetti)-Viral pneumonia-Histoplasmosis-Coccidiomycosis-Ruptured aortic aneurysm-SVC syndrome-Silicosis-Sarcoidosis ==Imaging==CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis ==Treatment==Cipro 500 mg bid or 30 mg/kg div q12Levo 500 mg qdDoxycycline 100 mg bidx 60 days PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks ==Source ==7/2/09 PANI
+==Background ==
+Gm positive rod, tough spores
+Inhalational Anthrax: Russian accident at Sverdlovsk
+-Incubation Period is 10 days
+-No one < 24 died
+==Ddx==
+Cutaneous (painless):
+-Ecthyma gangrenosum
+-Rat-bite fever (Streptobacillus monilifomis and Spirillum minus)
+-Ulceroglandular tularemia
+-Plague
+-Glanders (Pseudomonas peudomallei)
+-Rickettsialpox (Rickettsia akari)
+-Orf (parapox virus)
+-Staph lymphadenitis
+-TB
+-Leprosy
+-Buruli ulcer (Mycobact ulcerans)
+Inhalational:
+-Acute bacterial mediastinitis
+-Mycoplasma
+-Legionnaire's
+-Psittacosis
+-Tularemia
+-Q fever (Coxiella burnetti)
+-Viral pneumonia
+-Histoplasmosis
+-Coccidiomycosis
+-Ruptured aortic aneurysm
+-SVC syndrome
+-Silicosis
+-Sarcoidosis
+==Imaging==
+CXR/CT- Widened mediastinum representing hemorrhagic mediastinitis
+==Treatment==
+Cipro 500 mg bid or 30 mg/kg div q12
+Levo 500 mg qd
+Doxycycline 100 mg bid
+x 60 days
+PLUS vaccine: inactivated, cell-free immediately, 2 wks and then 4 wks
+==Source ==
+/2/09 PANI