Tocilizumab

Administration

  • Type: IL-6 antagonist
  • Dosage Forms:
  • Routes of Administration:
  • Common Trade Names:

Adult Dosing

COVID

  • 8 mg/kg actual body weight (up to 800 mg) administered as a single IV dose

Pediatric Dosing

Special Populations

Pregnancy Rating

Lactation risk

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

Comments

  • Trials show that may improved survival and other clinical outcomes in patients in admitted severe disease
  • In clinical trials, a third of the participants received a second dose of tocilizumab 8 hours after the first dose if no clinical improvement was observed.

See Also

References