Template:Platelet transfusion indications

Platelet Transfusion Thresholds

most if not all of the following thresholds are based on weak recommendations with low quality evidence[1]

  • <50K if planned lumbar puncture or neurosurgical procedure[2]
  • <20K if planned for central venous catheter placement (preference toward compressible site), or febrile patient
  • <10K in asymptomatic patients (unless due to ITP, TTP, or HIT)

There are no firm recommendations for transfusion thresholds in acute traumatic bleeding but many providers will opt for a goal of 100K, especially if there is evidence of ICH

  1. Kaufman, R. et al. Platelet Transfusion: A Clinical Practice Guideline From the AABB. Annals of Internal Medicine. 2015. Vol 162. No. 3 205-214 Full Text
  2. Shuoyan, N. et al. Safety of Lumbar Punctures in Adult Oncology Patients with Thrombocytopenia. Blood 2015 126:1141