Template:Nicotine Clinical Features

Postive	Negative
Anxiolysis	Gastrointestinal Distress
Congnitive Enhancement	Hypothermia
Cerebrovasodilation	Emesis
Neuroprotection	Hypertension
Analgesia	Seizures
Antipscyhotic	Respiratory Distress

Eye Pain

• Nicotine is also an irritant and eye pain is a frequent complaint

Fasciculations

• Due to the neuromuscular nicotinic activation

Hypersalivation

At high doses nicotine will activate muscarinic receptors

Biphasic presentation

• Initially present with excitation, N/V/D, salivation, tachycardia, hypertension, diaphoresis
• Delayed presentation is hypotension, bradycardia, hypoventilation, fasiculations, seizures, coma, and death