Template:Infectious Tenosynovitis Antibiotics

Treatment should cover S. aureus, Streptococcus, and MRSA

• Vancomycin 25-30 mg/kg IV loading dose then 15-20mg/kg IV q12hrs PLUS
  • Levofloxacin 750 mg IV once daily (avoid in pediatrics) OR
  • Ceftriaxone 1g IV daily
• If suspicious of Gonococcal infection then use Ceftriaxone 1g IV once daily AND Chlamydia coverage with
  • Azithromycin 1g PO once OR
  • Doxycycline 100mg PO twice daily

Animal Bites

• Ampicillin/Sulbactam 3g (50mg/kg) IV four times daily

Pediatrics

• Ceftriaxone 100mg/kg IV once daily AND Metronidazole 7.5mg/kg IV four times daily OR
• Clindamycin 10mg/kg IV four times daily AND TMP/SMX 5mg/kg IV BID
• Ampicillin/Sulbactam 50 mg/kg IV four times daily

Mycobacteria related

Treatment should include usual therapy listed above in addition to:

• Clarithromycin 500mg PO twice daily PLUS
  • Ethambutol 15 mg/kg PO once daily OR
  • Rifampin 600 mg PO once daily AND consult infectious disease