Temazepam

Administration

  • Type: Benzodiazepine
  • Dosage Forms: Cap 7.5mg, 15mg, 22.5mg, 30mg
  • Routes of Administration: Oral
  • Common Trade Names: Restoril

Adult Dosing

Insomnia

  • 15mg PO qhs
    • Start 7.5mg PO qhs in elderly patients

Sleep terrors

  • 15-30mg PO qhs

Pediatric Dosing

Safety/efficacy not established in pediatric patients

Special Populations

Pregnancy Rating

  • Consider alternatives during pregnancy
  • Risk of neonatal withdrawal symptoms and floppy infant syndrome

Lactation risk

  • May use low doses short-term when breastfeeding

Renal Dosing

  • Adult: No adjustment
  • Pediatric: Not defined

Hepatic Dosing

  • Adult: No adjustment
  • Pediatric: Not defined

Contraindications

  • Allergy to class/drug
  • Pregnancy
  • Avoid abrupt withdrawal with long term use

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life: 8.8h
  • Metabolism: Liver
  • Excretion: Urine 80-90%

Mechanism of Action

Comments

See Also

Benzodiazepine

References

Authors:

Jonathan Warren