Spinosad

Administration

  • Type: Pediculicide
  • Dosage Forms:
  • Routes of Administration: Topical
  • Common Trade Names: Natroba

Adult Dosing

  • Apply to dry hair/scalp, rinse after 10m

Pediatric Dosing

  • <6mo: do not use
  • >6mo: apply to dry hair/scalp, rinse after 10m

Special Populations

Pregnancy Rating

  • Pregnancy Category B

Lactation risk

  • Pump/dump for 8h due to risk of benzyl alcohol systemic absorption

Renal Dosing

Hepatic Dosing

Contraindications

  • Allergy to class/drug
  • Infants <6mo (contains benzyl alcohol which is harmful to infants if absorbed

Adverse Reactions

Serious

Common

  • Application site erythema, irritation, dryness, exfoliation
  • Ocular erythema/hyperemia
  • Alopecia
  • Dry skin

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • "Causes neuronal excitation in insects, followed by hyperexcitation, paralysis, and death" (!)[1]

Comments

See Also

References