Ribavirin

(Redirected from Ribavarin)

Administration

Adult Dosing

  • 200-1000mg daily (dose depends on genotype and concurrent treatment with interferon)

Pediatric Dosing

  • Hep C: >2 years old: 15mg/kg daily OR 400-1200mg daily
  • RSV (severe cases): 20mg/ml aerosolized over 12-18 hours x 3-7 days

Special Populations

Contraindications

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life: ~300 hours
  • Metabolism:
  • Excretion: Mostly renal

Mechanism of Action

  • Mechanism not well understood

Comments

See Also

References