Reteplase

(Redirected from Retavase)

Administration

  • Type: Thrombolytic
  • Dosage Forms: injection
  • Routes of Administration: IV
  • Common Trade Names: Retavase

Indications

Adult Dosing

  • 10 units IVx2

Pediatric Dosing

  • Not approved for use in pediatrics

Special Populations

Pregnancy Rating

  • Category C

Lactation risk

  • Caution advised while breastfeeding

Renal Dosing

  • Adult: n/a

Hepatic Dosing

  • Adult: n/a

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

  • Bleeding

Pharmacology

  • Half-life: 13-16 min
  • Metabolism: Liver, kidney

Mechanism of Action

  • Binds to fibrin, converts tissue plasminogen to plasmin, promoting thrombolysis[1]


See Also


References

  1. Reteplase [monograph]. Epocrates Version. 20.2 [iPhone]. Epocrates, Inc, San Francisco, CA. Available from https://online.epocrates.com/. Accessed March 26, 2020.